Whole blood volume determined by radiochromium-tagged red cells; comparative studies on normal and congestive heart failure patients.

The effect of congestive heart failure on blood volume as determined by radiochromium-tagged red cells.

Whole Blood Volume Determined by Radiochromium - Tagged Red Cells

IN CONGESTIVE heart failure the blood volume has generally been considered to be elevated." 6, 14, 15, 16, 18, 21t 24 Recent investigations by Prentice and co-workers19 and by Ross and associates,20 using P32-tagged erythrocytes, have suggested that the blood volume in heart failure often is not increased. The importance of hypervolemia in both the physiology and therapy of cardiac failure has ...

Blood Volume Alterations in Congestive Heart

A considerable body of data indicates that the plasma volume, as measured by dye dilution methods, is generally increased in congestive heart failure (1-4). However, recent investigations, utilizing p82 (5, 6) or Cr51 (7) tagged red cells, indicate that there is little or no increase in total blood volume, plasma volume, or red cell volume in most cases of heart failure. According to presently ...

Change in relationship of blood volume to weight in congestive heart failure.

Blood volume has been estimated in a small group of nonedematous hospitalized patients and in (arldiac patients in severe congestive failure by both Cr5'-labeled red cells and iodinated (P'31) human serum albumin. In the analysis of the data attention is directed to a fallacy inherent in the usual ratio method of relating blood volume to weight. An alternative method of analysis is proposed tha...

Congestive heart failure: fifty years of progress.

Volume 1 of Circulation provides an excellent snapshot of the understanding of the mechanisms and treatment of heart failure a half century ago. During that era, circulatory pathophysiology was at the center of investigative attention. For example, Tinsley Harrison and his group divided heart failure into “primary disorders of filling and primary disorders of emptying,”1 a forerunner of our cur...